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Signal failure

Signal failure

作者:巨先替  时间:2019-03-08 09:08:02  人气:

THE inability to make just one of many immune signalling molecules called cytokines can render a person vulnerable to infection by bacteria that are usually harmless. An international team of researchers studied a child with an inherited gene defect that prevents production of a cytokine called interleukin-12. The child has suffered serious infections from types of mycobacteria that normally only cause illness in people who have severely compromised immune systems (The Journal of Clinical Investigation, vol 102, p 2035). The results support earlier evidence that IL-12 is crucial in warding off mycobacteria,